In recent years, the United States Food and Drug Administration (FDA) granted Class 1 or 2 device clearance to serious games or game-like technologies. This trend encourages worldwide game designers and developers to explore the potential of serious games for various usages in health since the Northern American pharmaceutical generated more than USD 1 trillion annual revenues since 2014. Such phenomenon attracts venture capitalists to fund game-related projects, which in turn facilitating interdisciplinary cooperation and collaboration between serious game experts and professionals in the medical sciences. In this session, Wee Hoe will share his experiences as a FY2017/2018 Humphrey fellow from Malaysia in the College of Education in Pennsylvania State University and the School of Medicine in Yale University. In particular, he will explain how the above-mentioned trend may have a positive impact on how medical practitioners may use or develop games as digital medicine.